31ST
A-IMBN/AMBO INTERNATIONAL TRAINING COURSE
- Lectures and Laboratory Practice on
Molecular Vaccinology -
International Vaccine Institute - Seoul,
Korea
June 2-6, 2008
█ Course Objectives and Description
The overall objective of this course is to
provide an overview of basic principles governing
the initial stages involved in the design
of vaccines, from their initial conception
to their evaluation in animals and in humans.
The first part of the course will review the
molecular and cellular mechanisms involved
in the homeostatic regulation of innate and
adaptive immunity, and why knowledge of such
mechanisms is important in designing appropriate
vaccine formulations, including adjuvants.
The second part of this course will review
current as well as novel vaccines, including
gene-based vaccines, against major bacterial,
viral and parasitic pathogens. The third part
of the course will be related to practical
and technical issues that are needed for the
pre-clinical and clinical evaluation of vaccine
candidates.
Laboratory bench activities will be carried
out under the supervision of expert instructors
and will involve practical demonstrations
of techniques employed to explore immune responses
induced by vaccines, and a short overview
of the critical stages involved in the production
and quality control of vaccines.
The format of this course will thus be a blend
of theoretical lectures and laboratory demonstrations
and has been chosen to facilitate interaction
between students and teachers
█ Lecturers and lab instructors
Prof. Y.C. Sung, Cecil Czerkinsky, MiNa Kweon,
Nathalie Mielcarek, Huan Huu Nguyen, Dong
Wook Kim, Konrad Stalder, Giulietta Saletti,
Rodney Carbis, Greg Smith and more
█ Organizers
International Vaccine Institute (IVI)
Asia-Pacific International Molecular Biology
Network (A-IMBN)
Asia Molecular Biology Organization (AMBO)
█ Participants
15-16 students including senior graduate students,
postdoctoral fellows, and junior faculty members
from Asia-Pacific region. Applicants will
be informed of their acceptance by May 2,
2008 by e-mail. The successful candidates
will be provided with an economy class airfare
to Korea (up to US$800) and their accommodations
at the Seoul National University Guest House
and meals during the course will be offered
by organizers.
█ Application Deadline: April 25, 2008
Applicants are required to send their application
form (download
 )
to Ms. Pilim Choi, International Vaccine Institute
(Tel: 82-2-881-1157) by email: pchoi@ivi.int
and Ms. Hyunjung Lee, A-IMBN Secretariat (Tel:
82-2-872-8016) by email: hjlee@a-imbn.org.
| |
• Please also send
us a letter and curriculum vitae outlining
your career, including reasons why you
would benefit from taking the course
(in 1-2 pages)
• If there
are more than 16 applicants, organizers
will use discretion to select final
participants based on the following
documents (CV and a letter of intention)
provided by the applicants. |
█ Course schedule
| Day
1
A.M., Mon. June 2
|
|
|
| |
Welcome and Introduction |
| |
Immunology Part I: general |
Prof. Cecil Czerkinsky |
Break |
| |
Immunology Part II: mucosal |
Dr. MiNa Kweon |
Lunch
(Note: after lunch the class will
be divided into two groups) |
Day
1
P.M., Mon. June 2 |
|
|
|
Group A |
FACS (Fluorescence-Activated
Cell Sorting)
for enumerating subpopulations of lymphocytes;
intra-cellular staining of cytokine-containing
cells |
|
Group B |
ELISpot (Enzyme-linked
Immunosorbent Spot assay)
for detection of activated T cells |
| |
Day 2
A.M., Tue, June 3
|
|
|
| |
Vaccines against bacteria |
Dr. Dong Wook Kim |
Break |
| |
Vaccines against parasites |
Dr. Nathalie Mielcarek |
Lunch |
Day 2
P.M., Tue, June 3
|
|
|
Group A |
ELISpot (Enzyme-linked
Immunosorbent Spot assay)
for detection of activated T cells |
|
Group B |
FACS (Fluorescence-Activated
Cell Sorting)
for enumerating subpopulations of lymphocytes;
intra-cellular staining of cytokine-containing
cells |
Day 3
A.M., Wed, June 4
|
|
|
| |
Vaccines against viruses |
Dr. Konrad Stadler |
Break |
| |
Adjuvants for vaccines |
TBA |
Lunch |
Day 3
P.M., Wed, June 4
|
|
|
|
Group A |
ELISA (Enzyme-linked
immunosorbent assay)
for measurement of vaccine-specific
antibody responses: principle, design
and validation |
|
Group B |
Luminex Assay
for simultaneous measurements of multiple
cytokines and chemokines in biological
samples
Lab tour: Vaccine
process and Quality Control |
Day 4
A.M., Thur, June 5
|
|
|
| |
Gene-based vaccines |
Prof. Sung |
Break |
| |
Gene profiling of Immunocytes |
Affymetrix |
Lunch |
Day 4
P.M., Thur, June 5
|
|
|
|
Group A |
Luminex Assay
for simultaneous measurements of multiple
cytokines and chemokines in biological
samples
Lab tour: Vaccine
process and Quality Control |
|
Group B |
ELISA (Enzyme-linked
immunosorbent assay)
for measurement of vaccine-specific
antibody responses: principle, design
and validation |
Farewell
Dinner |
| Day 5. Sat, June
6 |
Tour on SNU campus |
|
|
